{"id":2175,"date":"2026-09-28T19:19:37","date_gmt":"2026-09-28T10:19:37","guid":{"rendered":"https:\/\/adpilatestimes.co.kr\/?p=2175"},"modified":"2026-09-28T19:19:37","modified_gmt":"2026-09-28T10:19:37","slug":"%ea%b1%b4%ea%b0%95%ed%95%9c-%eb%85%b8%ed%99%94%ec%9d%98-%ec%a7%80%eb%a6%84%ea%b8%b8-%ec%9a%b4%eb%8f%99%ec%9c%bc%eb%a1%9c-%ea%b7%bc%ec%9c%a1%ea%b3%bc-%ea%b0%84-%ea%b8%b0%eb%8a%a5%eb%8f%84-%ec%a7%80","status":"publish","type":"post","link":"https:\/\/adpilatestimes.co.kr\/?p=2175","title":{"rendered":"\uac74\uac15\ud55c \ub178\ud654\uc758 \uc9c0\ub984\uae38, \uc6b4\ub3d9\uc73c\ub85c \uadfc\uc721\uacfc \uac04 \uae30\ub2a5\ub3c4 \uc9c0\ucf1c\uc694"},"content":{"rendered":"<div class=\"div_right\">\n<table id=\"3\" class=\"__se_tbl table_inline\" summary=\"table\">\n<tbody>\n<tr>\n<td>\uac74\uac15\ud55c \ub178\ud654\uc758 \uc9c0\ub984\uae38, \uc6b4\ub3d9\uc73c\ub85c \uadfc\uc721\uacfc \uac04 \uae30\ub2a5\ub3c4 \uc9c0\ucf1c\uc694<\/td>\n<\/tr>\n<tr>\n<td>&#8211; \ub178\uc778\uc5d0\uc11c \uc6b4\ub3d9\uc744 \ud1b5\ud574 \uc99d\uac00\ub418\ub294 \uadfc\uac10\uc18c \uc5b5\uc81c \ud638\ub974\ubaac \u2018\ubc14\uc774\uae00\ub9ac\uce78\u2019\uc758 \ud6a8\uacfc \uaddc\uba85<\/p>\n<p>&#8211; \uadfc\uc721 \ubfd0\ub9cc\uc544\ub2c8\ub77c \ub178\ud654\ub85c \uc778\ud55c \uc9c0\ubc29\uac04 \uc644\ud654 \ud6a8\uacfc\uae4c\uc9c0 \ubcf4\uc5ec<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>&nbsp;<\/p>\n<p>\uc9c8\ubcd1\uad00\ub9ac\uccad(\uccad\uc7a5 \uc784\uc2b9\uad00) \uad6d\ub9bd\ubcf4\uac74\uc5f0\uad6c\uc6d0(\uc6d0\uc7a5 \uc9c1\ubb34\ub300\ub9ac \uae40\uc6d0\ud638)\uc740\u00a0\uc6b4\ub3d9\uc73c\ub85c \ubd84\ube44\ub418\ub294 \uadfc\uc721\ud638\ub974\ubaac \ubc14\uc774\uae00\ub9ac\uce78(Biglycan)\uc774 \ub178\ud654\ub85c \uc778\ud55c \uadfc\uac10\uc18c\uc99d\uacfc \uc9c0\ubc29\uac04\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uac1c\uc120\ud558\ub294 \ud6a8\uacfc\uac00 \uc788\uc74c\uc744 \ud655\uc778\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4. \uc774\ubc88 \uc5f0\uad6c \uacb0\uacfc\ub294 \uc758\uacfc\ud559 \ubd84\uc57c \uad6d\uc81c \ud559\uc220\uc9c0 \u300cInternational Journal of Molecular Sciences\u300d\uc5d0 \uc628\ub77c\uc778 \uac8c\uc7ac\u00a0\ub418\uc5c8\ub2e4(\ubd99\uc7841 \ucc38\uace0).<\/p>\n<p>\u203b \ub17c\ubb38\uba85: Biglycan alleviates age-related muscle atrophy and hepatocellular senescence<\/p>\n<p>&nbsp;<\/p>\n<p>\uad6d\ub0b4 \uba54\ud0c0\ubd84\uc11d \uc5f0\uad6c\uacb0\uacfc\uc5d0 \ub530\ub974\uba74, 65\uc138 \uc774\uc0c1 \ub178\uc778 13.1%\uac00 \uadfc\uac10\uc18c\uc99d\uc5d0 \ud574\ub2f9\ud558\ub294 \uac83\uc73c\ub85c \ud655\uc778\ub410\ub2e4. \ud2b9\ud788, 70~84\uc138 \ub178\uc778 \ub300\uc0c1 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ub0a8\uc131 21.3%, \uc5ec\uc131 13.8%\uac00 \uadfc\uac10\uc18c\uc99d\uc744 \uac16\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>\uadfc\uac10\uc18c\uc99d\uc740 \ub2e8\uc21c\ud55c \ub178\ud654 \ud604\uc0c1\uc774 \uc544\ub2c8\ub77c \ub098\uc774\uac00 \ub4e4\uba74\uc11c \uadfc\uc721\uc758 \uc591, \uadfc\ub825, \uadfc\uae30\ub2a5\uc774 \ube44\uc815\uc0c1\uc801\uc73c\ub85c \uac10\uc18c\ud558\ub294 \uc9c8\ud658\uc774\ub2e4. \uc774\ub294 \ud65c\ub3d9\uc7a5\uc560 \ubc0f \ub178\uc778\uc131 \ub9cc\uc131\uc9c8\ud658\uc744 \uc720\ubc1c\ud558\uace0 \uc608\ud6c4\ub97c \uc545\ud654\uc2dc\ud0a4\ub294 \uc704\ud5d8\uc778\uc790\ub85c \uc0ac\ub9dd \uc704\ud5d8\uc744 \uc57d 3\ubc30 \uc774\uc0c1 \ub192\uc5ec \uac74\uac15\ud55c \ub178\ub144 \uc0dd\ud65c\uc744 \uc704\ud611\ud55c\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>\uad6d\ub9bd\ubcf4\uac74\uc5f0\uad6c\uc6d0 \ub0b4\ubd84\ube44\u00b7\uc2e0\uc7a5\uc9c8\ud658\uc5f0\uad6c\uacfc \uc5f0\uad6c\uc9c4\uc740\u00a0\ubbf8\uad6d \uad6d\ub9bd\uc0dd\ubb3c\uacf5\ud559\uc815\ubcf4\uc13c\ud130(NCBI) \uc804\uc0ac\uccb4 \uc624\ud508 \ub370\uc774\ud130\uc14b \ubc0f \ud608\uc7a5 \ub2e8\ubc31\uccb4 \ubd84\uc11d\uc744 \ud1b5\ud574, \ub178\ud654\ub85c \uc778\ud574 \uac10\uc18c\ud558\ub294 \uadfc\uc721 \ud638\ub974\ubaac\uc778 \ub9c8\uc774\uc624\uce74\uc778(myokine)*\uc5d0 \ucd08\uc810\uc744 \ub9de\ucdb0 \uadfc\uac10\uc18c\uc99d \uac1c\uc120 \ud6a8\uacfc\ub97c \ud655\uc778\ud558\uace0\uc790 \ud558\uc600\ub2e4. \uadf8 \uacb0\uacfc, \ub178\uc778\uc758 \uadfc\uc721\uacfc \ud608\uc561\uc5d0\uc11c \ub9c8\uc774\uc624\uce74\uc778 \uc911 \ud558\ub098\uc778 \ubc14\uc774\uae00\ub9ac\uce78\uc758 \uc591\uc774 \ud06c\uac8c \uc904\uc5b4 \uc788\uc74c\uc744 \ud655\uc778\ud588\ub2e4.<\/p>\n<p>* \ub9c8\uc774\uc624\uce74\uc778(myokine)\uc740 \uc6b4\ub3d9\uc744 \ud1b5\ud574 \uadfc\uc721\uc5d0\uc11c \uc0dd\uc131\ub3fc \ud608\uc561\uc73c\ub85c \ubd84\ube44\ub418\ub294 \ud638\ub974\ubaac\uc744 \uc9c0\uce6d, \uadfc\uae30\ub2a5\uc744 \uac15\ud654\uc2dc\ud0a4\uace0,\uccb4\ub0b4 \uc5fc\uc99d\uacfc \uba74\uc5ed\ub825 \uc870\uc808, \ub1cc\uae30\ub2a5 \ud5a5\uc0c1\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud568<\/p>\n<p>\uc950\ub97c \uc774\uc6a9\ud55c \uc2e4\ud5d8\uc5d0\uc11c \uc80a\uc740 \uc950\uc5d0 \ube44\ud574 \ub178\ud654\ub41c \uc950\ub294 \ud608\uc561 \ubc0f \uadfc\uc721\uc5d0\uc11c \ubc14\uc774\uae00\ub9ac\uce78 \uc591\uc774 \uac10\uc18c\ub418\uc5b4 \uc788\uc5c8\uace0, \ub178\ud654\ub41c \uc950\ub97c 4\uac1c\uc6d4\uac04 \uc6b4\ub3d9 \uc2dc\ud0a8 \uacb0\uacfc \uadfc\uae30\ub2a5\uc774 \uac1c\uc120\ub418\uace0 \ubc14\uc774\uae00\ub9ac\uce78 \uadfc\uc721 \uc591\uc774 \uc99d\uac00\ud558\ub294 \uac83\uc744 \ud655\uc778\ud558\uc600\ub2e4. \ub610\ud55c, \uc6b4\ub3d9\uc744 \ud1b5\ud574 \uc99d\uac00\ub41c \ubc14\uc774\uae00\ub9ac\uce78\uc774 \uadfc\ub2e8\ubc31\uc9c8 \ud569\uc131\uc744 \ucd09\uc9c4\uc2dc\ucf1c \uadfc\uac10\uc18c\ub97c \uc644\ud654\uc2dc\ud0a8\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1d\ud600\ub0c8\ub2e4.<\/p>\n<table id=\"4\" class=\"__se_tbl table_inline\" summary=\"table\">\n<colgroup>\n<col \/><\/colgroup>\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.korea.kr\/docViewer\/result\/2026.04\/03\/b94d6366fee4a66a018a70b34f073522\/b94d6366fee4a66a018a70b34f073522.files\/image5_effect.jpg\" alt=\"\uadf8\ub9bc\uc785\ub2c8\ub2e4. \uc6d0\ubcf8 \uadf8\ub9bc\uc758 \uc774\ub984: \uc6b4\ub3d9\uc744-\ud1b5\ud574-\ubd84\ube44\ub41c-\ubc14\uc774\uae00\ub9ac\uce78(Biglycan)\uc758-\uadfc\uc721\uacfc-\uac04-\uc190\uc0c1-\uac1c\uc120\ud6a8\uacfc-\ubaa8\uc2dd\ub3c4.jpg \uc6d0\ubcf8 \uadf8\ub9bc\uc758 \ud06c\uae30: \uac00\ub85c 2526pixel, \uc138\ub85c 1785pixel\" \/><\/td>\n<\/tr>\n<tr>\n<td>[\uadf8\ub9bc] \uc6b4\ub3d9\uc744 \ud1b5\ud574 \ubd84\ube44\ub41c \ubc14\uc774\uae00\ub9ac\uce78(Biglycan)\uc758 \uadfc\uc721\uacfc \uac04 \uc190\uc0c1 \uac1c\uc120\ud6a8\uacfc \ubaa8\uc2dd\ub3c4<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>\ud2b9\ud788, \uc774\ubc88 \uc5f0\uad6c\ub294 \uadfc\uc721\uc5d0\uc11c \ubd84\ube44\ub41c \ubc14\uc774\uae00\ub9ac\uce78\uc774 \uac04\uc73c\ub85c \uc774\ub3d9\ud558\uc5ec\u00a0\ub178\ud654\ub85c \uc778\ud55c \uc9c0\ubc29\uac04 \uc644\ud654\uc5d0 \uc601\ud5a5\uc744 \uc900\ub2e4\ub294 \uc0ac\uc2e4\uc744 \uaddc\uba85\ud588\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>\uc5f0\uad6c\uc9c4\uc740 \ubc14\uc774\uae00\ub9ac\uce78\uc774 \ub178\ud654\ub85c \uc778\ud55c \uadfc\uac10\uc18c\uc640 \uc9c0\ubc29\uac04\uc744 \ub3d9\uc2dc\uc5d0 \uc644\ud654\ud558\ub294 \ud575\uc2ec\uc778\uc790\uc784\uc744 \ud655\uc778\ud588\uc73c\uba70, \uc774\ubc88 \uacb0\uacfc\uac00 \ud5a5\ud6c4 \ud56d\ub178\ud654 \uc5f0\uad6c\uc640 \ub178\uc778\uc131 \ub9cc\uc131\uc9c8\ud658 \uc608\ubc29 \uc804\ub7b5 \ub9c8\ub828\uc5d0 \uc911\uc694\ud55c \uacfc\ud559\uc801 \uadfc\uac70\uac00 \ub420 \uac83\uc73c\ub85c \uae30\ub300\ud558\uace0 \uc788\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>\uae40\uc6d0\ud638 \uad6d\ub9bd\ubcf4\uac74\uc5f0\uad6c\uc6d0\uc7a5 \uc9c1\ubb34\ub300\ub9ac\ub294 \u201c\uae09\uc18d\ud55c \uace0\ub839\ud654\uc640 \ub178\uc778\uc131 \ub9cc\uc131\uc9c8\ud658 \uc99d\uac00\uc5d0 \ub300\uc751\ud558\uc5ec \ub178\uc778\uc758 \uadfc\uac10\uc18c \uc608\ubc29\uc758 \uc911\uc694\uc131\uc744 \ubc1d\ud788\ub294 \uc5f0\uad6c\u201d\ub77c\uba70 \u201c\uc55e\uc73c\ub85c \uad6d\ub9bd\ubcf4\uac74\uc5f0\uad6c\uc6d0\uc740 \ub178\uc778\uc131 \uc9c8\ud658 \uc608\ubc29\uad00\ub9ac \uc5f0\uad6c\ub97c \uc9c0\uc18d\uc801\uc73c\ub85c \ucd94\uc9c4 \ud560 \uac83\u201d\uc774\ub77c\uace0 \ubc1d\ud614\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>\uc784\uc2b9\uad00 \uc9c8\ubcd1\uad00\ub9ac\uccad\uc7a5\uc740 \u201c\uac74\uac15\ud55c \ub178\ud6c4\uc640 \uc0b6\uc758 \uc9c8\uc744 \ub192\uc774\uae30 \uc704\ud574\uc120 \uadfc\uac10\uc18c\uc99d \uc608\ubc29\uc774 \ud544\uc218\uc801\u201d\uc774\ub77c\uba70, \u201c\uc5b4\ub974\uc2e0\ub4e4\uc758 \uadfc\uc721 \uac74\uac15\uc744 \uc720\uc9c0\ud558\uae30 \uc704\ud574\uc11c\ub294 \uaca8\uc6b8\ucca0\uc5d0\ub3c4 \uac1c\uc778\uc5d0 \ub9de\ub294 \ub9de\ucda4\ud615 \uc6b4\ub3d9\uacfc \uc601\uc591\uad00\ub9ac\uac00 \ubcd1\ud589\ub418\uc5b4\uc57c \ud560 \uac83\u201d\uc774\ub77c\uace0 \ubc1d\ud614\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\uac74\uac15\ud55c \ub178\ud654\uc758 \uc9c0\ub984\uae38, \uc6b4\ub3d9\uc73c\ub85c \uadfc\uc721\uacfc \uac04 \uae30\ub2a5\ub3c4 \uc9c0\ucf1c\uc694 &#8211; \ub178\uc778\uc5d0\uc11c \uc6b4\ub3d9\uc744 \ud1b5\ud574 \uc99d\uac00\ub418\ub294 \uadfc\uac10\uc18c \uc5b5\uc81c \ud638\ub974\ubaac \u2018\ubc14\uc774\uae00\ub9ac\uce78\u2019\uc758 \ud6a8\uacfc \uaddc\uba85 &#8211; \uadfc\uc721 \ubfd0\ub9cc\uc544\ub2c8\ub77c <\/p>\n","protected":false},"author":15,"featured_media":2176,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15,45,2],"tags":[],"class_list":["post-2175","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-b5358446fec4ebd0d8fea6f6f37c252f1ae44b13034c0df8ac7586fab1e52f34ecb5358446fec4ebd0d8fea6f6f37c252f1ae44b13034c0df8ac7586fab1e52f34b0b5358446fec4ebd0d8fea6f6f37c252f1ae44b13034c0df8ac7586fab1e52f3","category-45","category-b5358446fec4ebd0d8fea6f6f37c252f1ae44b13034c0df8ac7586fab1e52f34ecb5358446fec4ebd0d8fea6f6f37c252f1ae44b13034c0df8ac7586fab1e52f34a3b5358446fec4ebd0d8fea6f6f37c252f1ae44b13034c0df8ac7586fab1e52f3"],"_links":{"self":[{"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=\/wp\/v2\/posts\/2175","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2175"}],"version-history":[{"count":1,"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=\/wp\/v2\/posts\/2175\/revisions"}],"predecessor-version":[{"id":2177,"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=\/wp\/v2\/posts\/2175\/revisions\/2177"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=\/wp\/v2\/media\/2176"}],"wp:attachment":[{"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2175"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2175"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/adpilatestimes.co.kr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}